The RNA-Binding Protein Quaking is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype
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چکیده
Eric P van der Veer, Ruben G de Bruin Adriaan O Kraaijeveld, Margreet R de Vries, Ilze Bot, Tonio Pera, Filip M Segers, Stella Trompet, Janine M van Gils, Marko K Roeten, Cora M Beckers, Peter J van Santbrink, Anique Janssen, Coen van Solingen, Jim Swildens, Hetty C de Boer, Erna A Peters, Roel Bijkerk, Mat Rousch, Merijn Doop, Martin Jan Schalij , Allard C van der Wal, Stéphane Richard, Theo J C van Berkel, J Geoffrey Pickering, Pieter S Hiemstra, Marie Jose Goumans, Ton J Rabelink, Antoine A F de Vries, Paul H A Quax, J Wouter Jukema, Erik A L Biessen and Anton Jan van Zonneveld 1,2
منابع مشابه
Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype.
RATIONALE RNA-binding proteins are critical post-transcriptional regulators of RNA and can influence pre-mRNA splicing, RNA localization, and stability. The RNA-binding protein Quaking (QKI) is essential for embryonic blood vessel development. However, the role of QKI in the adult vasculature, and in particular in vascular smooth muscle cells (VSMCs), is currently unknown. OBJECTIVE We sought...
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تاریخ انتشار 2013